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Easy Access to Quinolin-2(1H)-ones via a One-Pot Tandem Oxa-Michael–Aldol Sequence

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An efficient strategy for the synthesis of a variety of quinolin-2(1H)-one derivatives has been developed. The reaction proceeded from cinnamide derivatives via a tandem reaction in the presence of NaOH… Click to show full abstract

An efficient strategy for the synthesis of a variety of quinolin-2(1H)-one derivatives has been developed. The reaction proceeded from cinnamide derivatives via a tandem reaction in the presence of NaOH to afford the corresponding 2- quinolin-2(1H)-one derivatives in good to excellent yields.

Keywords: easy access; quinolin ones; access quinolin; ones via; one pot; via one

Journal Title: Synlett
Year Published: 2017

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