Novel aminoethyl-, aminopropyl-, and aminobutyl-substituted thiazole-4-carboxamides have been prepared which are ring-opened analogues of piperidinyl-thiazole fungicides. Depending of the chain length, completely different synthetic approaches had to be chosen which… Click to show full abstract
Novel aminoethyl-, aminopropyl-, and aminobutyl-substituted thiazole-4-carboxamides have been prepared which are ring-opened analogues of piperidinyl-thiazole fungicides. Depending of the chain length, completely different synthetic approaches had to be chosen which vary from a Sonogashira coupling with a 2-bromothiazole derivative to a thiazole ring construction from different β- and δ-amino acids.
Keywords:
thiazole fungicides;
ring opened;
synthesis ring;
piperidinyl thiazole;
opened analogues
Journal Title: Synlett
Year Published: 2017
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Journal Title: Synlett
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!