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Study of the Cross-Metathesis Reaction of α-Hydroxy β,γ-Unsaturated Amides towards a Rapid and Flexible Total ­Synthesis of Symbioramide and its Isomer

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The reactivity of novel α-hydroxy β,γ-unsaturated amides in cross-metathesis reactions was extensively studied and used to perform a short total synthesis of symbioramide and its isomer from ­ l -serine… Click to show full abstract

The reactivity of novel α-hydroxy β,γ-unsaturated amides in cross-metathesis reactions was extensively studied and used to perform a short total synthesis of symbioramide and its isomer from ­ l -serine methyl ester.

Keywords: symbioramide isomer; unsaturated amides; hydroxy unsaturated; total synthesis; synthesis symbioramide; cross metathesis

Journal Title: Synlett
Year Published: 2018

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