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N-Triflylphosphorimidoyl Trichloride: A Versatile Reagent for the Synthesis of Strong Chiral Brønsted Acids

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A series of strong Bronsted acids has been synthesized in high yields using N-triflylphosphorimidoyl trichloride as reagent. The syntheses proceed efficiently with electron-rich, electron-deficient, and sterically hindered substrates. Click to show full abstract

A series of strong Bronsted acids has been synthesized in high yields using N-triflylphosphorimidoyl trichloride as reagent. The syntheses proceed efficiently with electron-rich, electron-deficient, and sterically hindered substrates.

Keywords: versatile reagent; triflylphosphorimidoyl trichloride; trichloride versatile; strong chiral; reagent synthesis; synthesis strong

Journal Title: Synlett
Year Published: 2017

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