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This research reports the successful asymmetric synthesis of both a 9-hydroxy-5′-methoxy-1,4-benzodioxane framework and a highly functionalised benzofuran scaffold. Both synthetically desirable structures are the result of a Lewis acid catalysed… Click to show full abstract
This research reports the successful asymmetric synthesis of both a 9-hydroxy-5′-methoxy-1,4-benzodioxane framework and a highly functionalised benzofuran scaffold. Both synthetically desirable structures are the result of a Lewis acid catalysed addition of an aryl nucleophile to 1,4-benzodioxane hemiacetals and offer a route towards the synthesis of a number of naturally occurring neolignans.
Keywords:
addition;
benzodioxane;
synthesis benzodioxane;
benzofuran scaffolds;
benzodioxane benzofuran;
benzofuran
Journal Title: Synthesis
Year Published: 2017
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Journal Title: Synthesis
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!