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The catalyst-free Nazarov cyclization of aryl allenyl ketones under thermal condition is developed. Various densely functionalized 2,3-dihydroindanones or indenones are readily produced in moderate to excellent yields. Significantly, this procedure… Click to show full abstract
The catalyst-free Nazarov cyclization of aryl allenyl ketones under thermal condition is developed. Various densely functionalized 2,3-dihydroindanones or indenones are readily produced in moderate to excellent yields. Significantly, this procedure features high functional group tolerance and exclusive regioselectivity. The resulting substituted 2,3-dihydroindanones can be conveniently converted into valuable conjugated benzofulvene building blocks.
Keywords:
cyclization aryl;
nazarov cyclization;
catalyst free;
allenyl ketones;
aryl allenyl
Journal Title: Synthesis
Year Published: 2018
Link to full text (if available)
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Journal Title: Synthesis
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!