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Palladium-Catalyzed Asymmetric 1,4-Addition of Diarylphosphines to α,β-Unsaturated Sulfonamides

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A pincer palladium-catalyzed asymmetric 1,4-addition of diarylphosphines to α,β-unsaturated sulfonamides was realized for the synthesis of chiral sulfonamide phosphines with up to 98% ee under mild conditions. Click to show full abstract

A pincer palladium-catalyzed asymmetric 1,4-addition of diarylphosphines to α,β-unsaturated sulfonamides was realized for the synthesis of chiral sulfonamide phosphines with up to 98% ee under mild conditions.

Keywords: catalyzed asymmetric; unsaturated sulfonamides; diarylphosphines unsaturated; palladium catalyzed; asymmetric addition; addition diarylphosphines

Journal Title: Synthesis
Year Published: 2018

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