Photo from wikipedia
A conceptually new synthesis of pyridine rings by a [C4 + CN] assembly has been developed by applying a vinylogous version of the classic Blaise reaction. The zinc-mediated reaction of… Click to show full abstract
A conceptually new synthesis of pyridine rings by a [C4 + CN] assembly has been developed by applying a vinylogous version of the classic Blaise reaction. The zinc-mediated reaction of (het)aryl or alkyl nitriles with ethyl-4-bromocrotonate provided a variety of C(6)-substituted pyridin-2-ones in a single-step.
Keywords:
new synthesis;
blaise reaction;
pyridin ones;
reaction;
conceptually new
Journal Title: Synlett
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Synlett
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!