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Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further… Click to show full abstract
Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.
Keywords:
ureas via;
sulfonyl ureas;
dihydroisoquinoline;
dihydroisoquinoline sulfonyl;
indole dihydroisoquinoline;
synthesis indole
Journal Title: Synthesis
Year Published: 2018
Link to full text (if available)
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Journal Title: Synthesis
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!