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An efficient and practical method for the synthesis of 2-sulfonylquinolines through copper-catalyzed deoxygenative C2-sulfonylation of quinoline N-oxides with 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO) and phenyldiazonium tetrafluoroborates is demonstrated. Products with various… Click to show full abstract
An efficient and practical method for the synthesis of 2-sulfonylquinolines through copper-catalyzed deoxygenative C2-sulfonylation of quinoline N-oxides with 1,4-diazabicyclo[2.2.2]octane bis(sulfur dioxide) (DABSO) and phenyldiazonium tetrafluoroborates is demonstrated. Products with various substituents were obtained in moderate to high yields.
Keywords:
quinoline oxides;
deoxygenative sulfonylation;
sulfonylation quinoline;
catalyzed deoxygenative;
copper catalyzed;
synthesis sulfonylquinolines
Journal Title: Synthesis
Year Published: 2019
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Journal Title: Synthesis
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!