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A concise route for the t BuO2H/Cu(acac)2-mediated synthesis of 1-oxoisochromans is described. This includes: (i) oxidation of oxygenated o-allyl arylaldehydes and (ii) sequential intramolecular lactonization of the resulting olefin-containing benzoic… Click to show full abstract
A concise route for the t BuO2H/Cu(acac)2-mediated synthesis of 1-oxoisochromans is described. This includes: (i) oxidation of oxygenated o-allyl arylaldehydes and (ii) sequential intramolecular lactonization of the resulting olefin-containing benzoic acids. A plausible mechanism is proposed and discussed.
Keywords:
synthesis;
buo2h acac;
lactonization;
synthesis oxoisochromans;
allyl arylaldehydes;
acac mediated
Journal Title: Synthesis
Year Published: 2020
Link to full text (if available)
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Journal Title: Synthesis
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!