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A photocatalyzed intramolecular cyclization is developed for the synthesis of fluorenones. In this photoredox reaction, triphenylphosphine is used as an inexpensive and effective deoxygenative reagent for biarylcarboxylic acids to give… Click to show full abstract
A photocatalyzed intramolecular cyclization is developed for the synthesis of fluorenones. In this photoredox reaction, triphenylphosphine is used as an inexpensive and effective deoxygenative reagent for biarylcarboxylic acids to give acyl radicals, which quickly undergo intramolecular radical cyclization. Reactions in the presence of air and continuous flow photoredox technology demonstrate the generality and practicality of this process.
Keywords:
acylation biarylcarboxylic;
biarylcarboxylic acids;
intramolecular acylation;
direct deoxygenative;
deoxygenative intramolecular
Journal Title: Synlett
Year Published: 2020
Link to full text (if available)
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Journal Title: Synlett
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!