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Synthesis of (2S,3R,5R)-2-Azido-3,5-dihydroxynonadecane Sphingolipid Analogue

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A concise and highly efficient synthesis of an enigmol analogue has been achieved. The synthetic strategy features Jacobsen’s hydrolytic kinetic resolution (HKR) and epoxide opening by alkynyl boranes as the… Click to show full abstract

A concise and highly efficient synthesis of an enigmol analogue has been achieved. The synthetic strategy features Jacobsen’s hydrolytic kinetic resolution (HKR) and epoxide opening by alkynyl boranes as the key steps.

Keywords: synthesis azido; dihydroxynonadecane sphingolipid; azido dihydroxynonadecane; sphingolipid analogue; synthesis

Journal Title: Synthesis
Year Published: 2020

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