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Epilepsia Partialis Continua in Hyperosmolar Nonketotic Hyperglycemia

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Type 2 diabetes mellitus (T2DM) is often associated with hyperglycemic emergencies due to diet noncompliance, drug default, or rarely as initial presentation. Often hyperosmolar nonketotic hyperglycemia (HONK) occurs typically in… Click to show full abstract

Type 2 diabetes mellitus (T2DM) is often associated with hyperglycemic emergencies due to diet noncompliance, drug default, or rarely as initial presentation. Often hyperosmolar nonketotic hyperglycemia (HONK) occurs typically in elderly T2DMpatientwith severe dehydration and altered sensorium. Though T2DM is associated neurological complications like diabetic neuropathy, seizures occur mostly with hypoglycemia. Seizures are seen in around 25% of T2DM patients with changes in serum sodium or changes in osmolality. Local cerebral damage, cerebral microvascular lesions, metabolic factors, and gene mutations are also some other mechanisms postulated for the development of seizure in T2DM.1

Keywords: continua hyperosmolar; epilepsia partialis; hyperosmolar nonketotic; nonketotic hyperglycemia; partialis continua

Journal Title: Journal of Neurosciences in Rural Practice
Year Published: 2021

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