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A tertiary phosphine-mediated [3+2] cyclization reaction of ynones with fluorinated coumarin derivatives has been developed to give a series of coumarin-based CF3-containing furanones in moderate to good yields under mild… Click to show full abstract
A tertiary phosphine-mediated [3+2] cyclization reaction of ynones with fluorinated coumarin derivatives has been developed to give a series of coumarin-based CF3-containing furanones in moderate to good yields under mild reaction conditions. Preliminary investigation into their antitumor activities is also presented.
Keywords:
coumarin based;
phosphine mediated;
containing furanones;
mediated cyclization
Journal Title: Synlett
Year Published: 2022
Link to full text (if available)
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Journal Title: Synlett
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!