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A 70-year-old man reported a 2-year history of progressive gait imbalance and cognitive decline (memory, executive functions, and language impairment). A physical examina-tion revealed spastic ataxia without peripheral involvement. The… Click to show full abstract
A 70-year-old man reported a 2-year history of progressive gait imbalance and cognitive decline (memory, executive functions, and language impairment). A physical examina-tion revealed spastic ataxia without peripheral involvement. The patient worked with car battery solutions for 40 years, until 13 years ago. 1 He had several hospitalizations due to acute lead poisoning, with levels of lead in the blood and urinary delta-aminolevulinic acid of 162,8g/dl and 20mg/U (normal: up to 40g/dl and 4,5mg/U) respectively). Recent brain neuroimages showed typical fi ndings of saturnism ( ► Figure 1 ), 2 with normal bone pro fi le blood tests. There-fore, chronic lead poisoning should be remembered as an environmental cause of leukoencephalopathy. 2 – 5
Journal Title: Arquivos de Neuro-Psiquiatria
Year Published: 2022
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