LAUSR

Abstract Funding Acknowledgements Type of funding sources: None. Background In an aging population with cardiac implantable electronic devices (CIED), an increasing number of octogenarians and even nonagenarians present for lead extraction procedures. Those patients are considered as having an increased risk for surgical procedures including lead extraction. Purpose We here investigated in a large patient cohort safety and efficacy of transvenous lead extraction with powered extraction sheaths in octo- and nonagenerians. Methods A subgroup analysis of the German Laser Lead Extraction Registry (GALLERY) registry was performed. 499 patients were aged ≥80 years and included in this analysis. Primary extraction method was Laser lead extraction, with additional use of mechanical rotational sheaths or femoral snares, if necessary. Predictors for complications and mortality were evaluated in multivariate analysis. Results Mean patients age was 84.3±3.7 years, 27.1% were female. 1196 leads were treated. The median lead dwell time was 118.0 (78;167) months. Clinical procedural success rate was achieved in 97.6% of the cases. Procedural failure was observed in 2.1%. Overall complication rate was 4.4%, including 1.8% major- and 2.6% minor complications. BMI<20, was the only statistically significant predictor for procedure related complications. Procedure-related mortality was 0.8%, all-cause in-hospital mortality was 5.4%. Predictors for in-hospital mortality were systemic infection, BMI≤20 kg/m2, procedural complications and chronic kidney disease. Conclusion Laser lead extraction in octo- and nonagenarians, is safe and effective. BMI BMI≤20 kg/m2 was the only statistically significant predictor for procedural complications. According to our data, advanced age should not be considered as contraindication for laser lead extraction.