LAUSR

Digestive endoscopy is increasingly replacing surgery in the treatment of postoperative leaks and fistulas. However, treatment of patients with these conditions remains challenging with many different methods being currently tested [1]. Here we present a case of a 69-year-old man who underwent Hartmann sigmoidectomy in 2014 for perforated diverticulitis. In September 2016, he underwent stoma reversal with protective ileostomy because of tissue fragility in the area of the anastomosis. A month later, an anastomotic rectal fistula with pericolic abscess collection was confirmed on a computed tomography (CT) scan (▶Fig. 1). Because the collection was unresponsive to antibiotic treatment, the fistulous tract was later drained with a doublepigtail stent (▶Fig. 2). The stent was removed 4 months later and we performed endoscopic submucosal dissection (ESD) of the mucosal patch surrounding the fistulous orifice, in order to ensure maximal excision of the orifice mucosa and increase the chances of successful scarring of the fistula (▶Fig. 3; ▶Video1). The exposed area was subsequently closed using an over-the-scope clip (OTSC) system (Ovesco, Tübingen, Germany) (▶Fig. 4; ▶Video1). The procedure was considered a technical success; however, the protective ileal stoma was left in place until full confirmation of fistula resolution and normal colonic passage had been obtained. A follow-up CT scan after 2 months confirmed the absence of visible collections or residual fistulous tract (▶Fig. 5). The patient remained well and asymptomatic, and he was scheduled for follow-up colonoscopy and stoma reversal. There is no generally recommended approach to endoscopic closure of gastrointestinal fistulas. Although the OTSC system is becoming widely used in this setting, in the setting of chronic fistulas, long-term clinical success occurs in only about one-third of patients [2], and previous dissection of the fistula may enhance tissue scarring, as previously demonstrated in esophagotracheal fistulas [3, 4]. To summarize, ESD of a fistulous orifice can be a valuable additional tool that may increase the success rates of endoscopic fistula closure using the OTSC system.