In this Perspective Letter, we discuss the field of remote photonic bio-sensing and diagnosis while focusing on sensing involving spatial analysis of temporally varied defocused secondary speckle patterns. Collecting secondary… Click to show full abstract
In this Perspective Letter, we discuss the field of remote photonic bio-sensing and diagnosis while focusing on sensing involving spatial analysis of temporally varied defocused secondary speckle patterns. Collecting secondary speckle patterns that were back-reflected from an inspected tissue while properly defocusing the imaging lens allows us to measure nano-vibrations occurring in the tissue. The nano-vibration signal can serve as the common denominator for simultaneous estimation of many bio-medical parameters related to vital bio-signs, hematology, and hemodynamics. This can provide a powerful tool for comprehensive medical diagnosis.
               
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