LAUSR

Significance The manipulation of liquid droplets plays a crucial role in multidisciplinary applications. However, existing methods still face many challenges, such as short distance, low velocity, restricted operating conditions, the need for extra responsive additives in droplet, and so on. To circumvent these constraints, here we develop a droplet electrostatic tweezer to trap the liquid droplet or faithfully guide the droplet motion in a remote manner. Our method allows high flexibility and precision in manipulating droplets of different types, volumes, and numbers under different working conditions, such as in open and closed spaces and on flat and tilted surfaces as well as in oil medium, imparting various applications, such as high-throughput and high-sensitivity Raman detection. Various physical tweezers for manipulating liquid droplets based on optical, electrical, magnetic, acoustic, or other external fields have emerged and revolutionized research and application in medical, biological, and environmental fields. Despite notable progress, the existing modalities for droplet control and manipulation are still limited by the extra responsive additives and relatively poor controllability in terms of droplet motion behaviors, such as distance, velocity, and direction. Herein, we report a versatile droplet electrostatic tweezer (DEST) for remotely and programmatically trapping or guiding the liquid droplets under diverse conditions, such as in open and closed spaces and on flat and tilted surfaces as well as in oil medium. DEST, leveraging on the coulomb attraction force resulting from its electrostatic induction to a droplet, could manipulate droplets of various compositions, volumes, and arrays on various substrates, offering a potential platform for a series of applications, such as high-throughput surface-enhanced Raman spectroscopy detection with single measuring time less than 20 s.