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Lizards from warm and declining populations are born with extremely short telomeres

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Significance This study unraveled the impacts of accelerated aging as a corollary of climate-driven population decline. We found a transgenerational accumulation of telomere shortening implying that offspring were already born… Click to show full abstract

Significance This study unraveled the impacts of accelerated aging as a corollary of climate-driven population decline. We found a transgenerational accumulation of telomere shortening implying that offspring were already born “old.” We suggest that this process may exacerbate across generations, leading to an aging loop in the population. This model posits that telomere dynamics should represent a critical and promising molecular biomarker of population extirpation as well as a way to test the in situ efficiency of conservation decisions.

Keywords: warm declining; born extremely; populations born; lizards warm; declining populations; extremely short

Journal Title: Proceedings of the National Academy of Sciences of the United States of America
Year Published: 2022

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