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Hippocampus and temporal pole functional connectivity is associated with age and individual differences in autobiographical memory

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Significance Autobiographical memory includes the recollection of both episodic and semantic content, which has been shown to engage the default network. The present study examines how regions associated with the… Click to show full abstract

Significance Autobiographical memory includes the recollection of both episodic and semantic content, which has been shown to engage the default network. The present study examines how regions associated with the coordinated retrieval of different types of details are intrinsically connected to the default network and how these connectivity patterns in turn relate to autobiographical recall in younger and older adults. Connectivity within this circuit scaled with the tendency to recall one’s personal past with a balance of episodic and semantic detail. Young adults showed a distinct signature of connectivity related to more detailed recollection overall. Our findings provide a high-resolution map of connectivity within the default network and evidence for how variation in this map is sensitive to individual differences in autobiographical recollection.

Keywords: connectivity; individual differences; default network; differences autobiographical; autobiographical memory

Journal Title: Proceedings of the National Academy of Sciences of the United States of America
Year Published: 2022

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