Photo from wikipedia
Significance Plant diseases destroy ∼20 to 30% of annual crop production, contributing to global food insecurity. Discovering how pathogen effectors target host proteins to promote virulence is essential for understanding… Click to show full abstract
Significance Plant diseases destroy ∼20 to 30% of annual crop production, contributing to global food insecurity. Discovering how pathogen effectors target host proteins to promote virulence is essential for understanding pathogenesis and can be used for developing disease-resistant crops. Here, we reveal the structural basis of how an effector from the blast pathogen (AVR-Pii) binds a specific host target (rice Exo70) and how this underpins immune recognition. This has implications for understanding the molecular mechanisms of blast disease and for engineering new recognition specificities in plant immune receptors to confer resistance to a major crop pathogen.
Journal Title: Proceedings of the National Academy of Sciences of the United States of America
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!