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A common vesicle proteome drives fungal biofilm development

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Significance Candida species are commensal organisms commonly interacting in the same host niche. In the pathogenic state, they frequently grow as a biofilm, often in mixed infections. The present studies… Click to show full abstract

Significance Candida species are commensal organisms commonly interacting in the same host niche. In the pathogenic state, they frequently grow as a biofilm, often in mixed infections. The present studies observe a reliance upon common extracellular vesicle cargo for biofilm structure and function supporting interactions among species. The results reveal a vesicle cargo-driven coordination among Candida species during biofilm formation.

Keywords: common vesicle; vesicle proteome; biofilm; proteome drives; vesicle; drives fungal

Journal Title: Proceedings of the National Academy of Sciences of the United States of America
Year Published: 2022

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