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Montmorillonite K10-catalyzed synthesis of N-fused imino-1,2,4-thiadiazolo isoquinoline derivatives

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ABSTRACT A novel synthesis of N-fused imino-1,2,4-thiadiazolo derivatives is described. This approach involves the inexpensive, nontoxic, recoverable, and easy to handle montmorillonite K10 that catalyzes the coupling of 3-aminoisoquinolines and… Click to show full abstract

ABSTRACT A novel synthesis of N-fused imino-1,2,4-thiadiazolo derivatives is described. This approach involves the inexpensive, nontoxic, recoverable, and easy to handle montmorillonite K10 that catalyzes the coupling of 3-aminoisoquinolines and phenylisothiocyanates to afford the N-fused imino-1,2,4-thiadiazolo isoquinoline motifs in exemplary yields. The main attractions of this synthetic strategy were simple procedure and excellent yields. GRAPHICAL ABSTRACT

Keywords: synthesis fused; montmorillonite k10; fused imino; imino thiadiazolo

Journal Title: Synthetic Communications
Year Published: 2018

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