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ABSTRACT A greener approach for the synthesis of 4-oxo-4,5,6,7-tetrahydro indole derivatives has been achieved through Wang-OSO3H-mediated three-component reaction involving dimedone, phenacyl bromide, and primary amine in water. A variety of… Click to show full abstract
ABSTRACT A greener approach for the synthesis of 4-oxo-4,5,6,7-tetrahydro indole derivatives has been achieved through Wang-OSO3H-mediated three-component reaction involving dimedone, phenacyl bromide, and primary amine in water. A variety of indole derivatives were prepared using this operationally simple and straight forward methodology in acceptable yields. GRAPHICAL ABSTRACT
Keywords:
resin supported;
wang resin;
water;
supported sulfonic;
reaction;
sulfonic acid
Journal Title: Synthetic Communications
Year Published: 2018
Link to full text (if available)
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Journal Title: Synthetic Communications
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!