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ABSTRACT TEMPO/CuI was found to be an effective catalyst for the cross-coupling of indoles with benzylic amines affording the corresponding bis(indolyl)phenylmethanes under air atmosphere at room temperature in good to… Click to show full abstract
ABSTRACT TEMPO/CuI was found to be an effective catalyst for the cross-coupling of indoles with benzylic amines affording the corresponding bis(indolyl)phenylmethanes under air atmosphere at room temperature in good to excellent yields. The efficiency, easy workup, simplicity, and chemoselectivity of this protocol provide a green and low-cost procedure for the synthesis of these compounds. GRAPHICAL ABSTRACT
Keywords:
tempo cui;
bis indolyl;
coupling indoles;
indolyl phenylmethanes;
cross coupling
Journal Title: Synthetic Communications
Year Published: 2018
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Journal Title: Synthetic Communications
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!