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Zinc-catalyzed multicomponent reactions: Facile synthesis of fully substituted pyridines

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Abstract A first example of environmentally benign zinc complex catalyzed one-pot four-component reaction between malononitrile, ketone, ammonium acetate and aromatic aldehyde for the facile synthesis of fully substituted pyridines just… Click to show full abstract

Abstract A first example of environmentally benign zinc complex catalyzed one-pot four-component reaction between malononitrile, ketone, ammonium acetate and aromatic aldehyde for the facile synthesis of fully substituted pyridines just within 2 min in environmentally friendly solvent ethanol has been optimized. GRAPHICAL ABSTRACT

Keywords: fully substituted; substituted pyridines; facile synthesis; synthesis fully; zinc catalyzed

Journal Title: Synthetic Communications
Year Published: 2018

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