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Coumarin-1,2,3-triazole hybrid derivatives: Green synthesis and DFT calculations

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Abstract A series of new 1,2,3-triazole-coumarin hybrid system are synthesized from the click reaction between 3-azido coumarin and different aromatic terminal alkyne derivatives in a green manner. All compounds are… Click to show full abstract

Abstract A series of new 1,2,3-triazole-coumarin hybrid system are synthesized from the click reaction between 3-azido coumarin and different aromatic terminal alkyne derivatives in a green manner. All compounds are characterized by IR, NMR and UV-VIS spectroscopy. The experimental observations are further supported by DFT computational studies to investigate the effect of substituents at para position in these compounds. Graphical Abstract

Keywords: coumarin triazole; derivatives green; green synthesis; hybrid derivatives; triazole hybrid; synthesis dft

Journal Title: Synthetic Communications
Year Published: 2019

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