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Addition-elimination of nitroalkanes to 3-phenacylideneoxindoles—direct method for the synthesis of 3-alkenylphenacylidene-oxindoles

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Abstract The first addition-elimination of nitroalkanes to 3-phenacylideneoxindoles was developed, affording the corresponding 3-alkenylphenacylidene-oxindoles with high yields.The addition-elimination mechanism of 3-phenacylideneoxindoles with nitroalkanes and removable NO2 group in concert guarantees… Click to show full abstract

Abstract The first addition-elimination of nitroalkanes to 3-phenacylideneoxindoles was developed, affording the corresponding 3-alkenylphenacylidene-oxindoles with high yields.The addition-elimination mechanism of 3-phenacylideneoxindoles with nitroalkanes and removable NO2 group in concert guarantees the high regioselectivity. GRAPHICAL ABSTRACT

Keywords: addition; nitroalkanes phenacylideneoxindoles; addition elimination; alkenylphenacylidene oxindoles; elimination nitroalkanes

Journal Title: Synthetic Communications
Year Published: 2019

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