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Easy installation of 1,2,3-triazoles or iodo-1,2,3-triazoles onto indole-fused oxazinones via CuAAC-based MCR in the presence of 18-crown-6

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Abstract An efficient protocol was developed to prepare indole-fused oxazinones using silver nitrate. The latter substrates were subjected to multicomponent reactions in the presence of 18-crown-6, which afforded diverse new… Click to show full abstract

Abstract An efficient protocol was developed to prepare indole-fused oxazinones using silver nitrate. The latter substrates were subjected to multicomponent reactions in the presence of 18-crown-6, which afforded diverse new heterocycles based on an indole-fused oxazinone-1,2,3-triazole scaffold. GRAPHICAL ABSTRACT

Keywords: presence crown; indole; indole fused; fused oxazinones

Journal Title: Synthetic Communications
Year Published: 2019

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