Photo by teveir from unsplash
Abstract A novel and highly efficient heterogeneous gold(I)-catalyzed cyclization between ynals and amidines has been developed that proceeds smoothly under mild conditions and provides a general and practical method for… Click to show full abstract
Abstract A novel and highly efficient heterogeneous gold(I)-catalyzed cyclization between ynals and amidines has been developed that proceeds smoothly under mild conditions and provides a general and practical method for the synthesis of a wide variety of 2,4-disubstituted pyrimidines with high atom-economy, good to high yield, and recyclability of the gold(I) catalyst. The present method is an attractive alternative to construct substituted pyrimidines. GRAPHICAL ABSTRACT
Keywords:
catalyzed cyclization;
cyclization ynals;
heterogeneous gold;
gold;
gold catalyzed;
ynals amidines
Journal Title: Synthetic Communications
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Synthetic Communications
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!