Abstract A series of flavonoid derivatives were synthesized from 6- and 8-iodo-3,7,3’4’-tetramethoxy-quercetin with terminal alkenes by microwave-assisted palladium-catalyzed Heck coupling. These alkenes include n-butyl acrylate, 2-methyl-3-buten-2-ol, acrylonitrile, and styrene, providing… Click to show full abstract
Abstract A series of flavonoid derivatives were synthesized from 6- and 8-iodo-3,7,3’4’-tetramethoxy-quercetin with terminal alkenes by microwave-assisted palladium-catalyzed Heck coupling. These alkenes include n-butyl acrylate, 2-methyl-3-buten-2-ol, acrylonitrile, and styrene, providing 10 new substituted flavonoid compounds obtained with moderate to good yields. Graphical Abstract
Keywords:
synthesis new;
alkenyl tetramethoxyquercetin;
heck coupling;
microwave assisted;
new alkenyl
Journal Title: Synthetic Communications
Year Published: 2019
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Journal Title: Synthetic Communications
Year Published: 2019
Link to full text (if available)
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recommendations!