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Abstract Efficient chemoselective oxidation of primary alcohols to the corresponding aldehydes is described. The transformation is promoted by a catalytic morpholinone nitroxide radical catalyst which can be easily synthesized. A… Click to show full abstract
Abstract Efficient chemoselective oxidation of primary alcohols to the corresponding aldehydes is described. The transformation is promoted by a catalytic morpholinone nitroxide radical catalyst which can be easily synthesized. A broad range of substrates including aromatic and aliphatic primary alcohols are converted with excellent yields under mild conditions. The control experiments reveal that the morpholinone nitroxide can be used as a selective oxidant for primary alcohols in the presence of secondary alcohols. Graphical Abstract
Journal Title: Synthetic Communications
Year Published: 2019
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