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Abstract Methyl-2-(3-oxo-3-aryl) benzoates derived from acid catalyzed air oxidative fragmentation of 2-aryl-1-tetralones were efficiently undergone intramolecular-Claisen condensation in the presence of potassium tertiary butoxide. The resulting 2-benzoyl-1-indanones formed in two-step… Click to show full abstract
Abstract Methyl-2-(3-oxo-3-aryl) benzoates derived from acid catalyzed air oxidative fragmentation of 2-aryl-1-tetralones were efficiently undergone intramolecular-Claisen condensation in the presence of potassium tertiary butoxide. The resulting 2-benzoyl-1-indanones formed in two-step ring contractions were further subjected to indium triflate mediated retro-Claisen condensation to get 1-indanones. Graphical Abstract
Keywords:
concise synthesis;
indanones aryl;
benzoyl indanones;
synthesis benzoyl;
indanones indanones;
aryl tetralones
Journal Title: Synthetic Communications
Year Published: 2020
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Journal Title: Synthetic Communications
Year Published: 2020
Link to full text (if available)
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recommendations!