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A new approach for the production of multifilament suture - in vitro and in vivo analysis

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Abstract We investigated, unique multifilament suture (UMS) was prepared from animal skin fiber (ASF) and cotton fiber (CF), which can be used for external surgeries and wound-healing applications. The distinctive… Click to show full abstract

Abstract We investigated, unique multifilament suture (UMS) was prepared from animal skin fiber (ASF) and cotton fiber (CF), which can be used for external surgeries and wound-healing applications. The distinctive properties of the UMS is that it shows tensile strength of 85.25 ± 0.09 (Mpa), 81.9 ± 0.46 (%) as elongation at break, 7.59 ± 0.26 (kgf) knot strength, 58.95 ± 0.55 (%) of flexibility and water absorption of about 51.03 ± 0.63 (%). In vitro study, performed its biocompatible in nature and in vivo experiments exhibited accelerated suturing and wound-healing properties. Graphical Abstract

Keywords: vivo; multifilament suture; suture; new approach; vitro; approach production

Journal Title: International Journal of Polymeric Materials and Polymeric Biomaterials
Year Published: 2020

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