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Reductive responsive hyaluronic acid conjugated S-nitrothiol prodrugs as drug carriers

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S-nitroso-N-acetylpenicillamine (SNAP) and hydrophobic succinyl pyrene (SuPy) were conjugated to hyaluronic acid (HA) through cystamine dihydrochloride (Cys) linkers to synthesize NO-conjugated red... Click to show full abstract

S-nitroso-N-acetylpenicillamine (SNAP) and hydrophobic succinyl pyrene (SuPy) were conjugated to hyaluronic acid (HA) through cystamine dihydrochloride (Cys) linkers to synthesize NO-conjugated red...

Keywords: conjugated nitrothiol; responsive hyaluronic; acid conjugated; reductive responsive; hyaluronic acid; acid

Journal Title: International Journal of Polymeric Materials and Polymeric Biomaterials
Year Published: 2021

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