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Bayesian comparison of diagnostic tests with largely non-informative missing data

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ABSTRACT This work was motivated by a real problem of comparing binary diagnostic tests based upon a gold standard, where the collected data showed that the large majority of classifications… Click to show full abstract

ABSTRACT This work was motivated by a real problem of comparing binary diagnostic tests based upon a gold standard, where the collected data showed that the large majority of classifications were incomplete and the feedback received from the medical doctors allowed us to consider the missingness as non-informative. Taking into account the degree of data incompleteness, we used a Bayesian approach via MCMC methods for drawing inferences of interest on accuracy measures. Its direct implementation by well-known software demonstrated serious problems of chain convergence. The difficulties were overcome by the proposal of a simple, efficient and easily adaptable data augmentation algorithm, performed through an ad hoc computer program.

Keywords: bayesian comparison; largely non; diagnostic tests; non informative; tests largely; comparison diagnostic

Journal Title: Journal of Statistical Computation and Simulation
Year Published: 2019

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