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Pregnancy complicated by ovarian planoepithelial carcinoma arising in mature cystic teratoma

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An adnexal tumour can be expected in 2–10% of pregnancies. A mature cystic teratoma (MCT) constitutes 10–20% of all ovarian tumours and is the most frequent germ cell tumour of… Click to show full abstract

An adnexal tumour can be expected in 2–10% of pregnancies. A mature cystic teratoma (MCT) constitutes 10–20% of all ovarian tumours and is the most frequent germ cell tumour of the ovary. The incidence of a malignant transformation in an MCT appears in 0.17–2% cases. The most frequent malignancy in an MCT is a planoepithelial carcinoma (squamous cell carcinoma) – 80–90% of cases (Hackethal et al. 2008). The malignant transformation of an MCT to a planoepithelial carcinoma in pregnancy is very rare. We found only two cases in the literature (Mekaru et al. 2008; Budiman et al. 2010). Although the management of ovarian tumours during a pregnancy is similar to the treatment in the case of nonpregnant patients, far more new studies are needed to confirm the most optimal management, due to the absence of standard recommendations. Case reports provide significant data on the management of these cancers (Palmer et al. 2009; Aggarwal and Kehoe 2011). We report an extremely rare case of a maternal planoepithelial carcinoma (G2) in a dermoid cyst detected during a caesarean section.

Keywords: carcinoma; pregnancy; planoepithelial carcinoma; cystic teratoma; mature cystic

Journal Title: Journal of Obstetrics and Gynaecology
Year Published: 2019

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