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Acellular cadaveric dermal matrix grafts for orbital wall reconstruction in patients with sinonasal malignancies

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ABSTRACT Purpose To describe the utilization of acellular cadaveric dermal matrix (ACDM) in patients undergoing orbital wall reconstruction after orbital preservation surgery for sinonasal malignancy. Methods Retrospective case series of… Click to show full abstract

ABSTRACT Purpose To describe the utilization of acellular cadaveric dermal matrix (ACDM) in patients undergoing orbital wall reconstruction after orbital preservation surgery for sinonasal malignancy. Methods Retrospective case series of seven patients with sinonasal malignancy who had orbital reconstruction with ACDM implants from January 2012 to August 2020. Orbital preservation was performed in all patients with tumor extension up to and including periorbital. The main outcome measures were implant exposure, orbital infection, diplopia in primary gaze, enophthalmos, and eyelid malposition. Results Patients ranged 37–78 years old (median: 66 years) and included 4 females and 3 males. The median follow-up time was 9 months (range 6–43 months) from the date of surgery. Squamous cell carcinoma comprised the majority of tumors with all patients needing medial wall reconstruction. Three patients received postoperative radiation therapy. No patients had any implant exposure, orbital infection, enophthalmos, or eyelid malposition. Conclusions ACDM grafts can be used safely in orbital wall reconstruction in patients with sinonasal malignancies.

Keywords: patients sinonasal; acellular cadaveric; wall reconstruction; reconstruction; cadaveric dermal; orbital wall

Journal Title: Orbit
Year Published: 2022

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