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ABSTRACT A series of alkyl triazole glycoside surfactants, ATGs, differing in the length of the alkyl linker between the sugar and the triazole, was synthesized and investigated on their surfactant… Click to show full abstract
ABSTRACT A series of alkyl triazole glycoside surfactants, ATGs, differing in the length of the alkyl linker between the sugar and the triazole, was synthesized and investigated on their surfactant properties and phase behavior in water. The results indicate no significant impact of the linker on surface and interphase properties, whereas the phase behavior is affected. Higher affinity for the bicontinuous cubic phase potentially favors methylene-linked ATGs over higher homologs for drug-delivery applications. A comparison of glucose and xylose reveals a tendency for high Krafft points for propargyl xyloside based ATGs. This disfavors these surfactants with respect to both glucose analogs and higher homologs. GRAPHICAL ABSTRACT
Journal Title: Journal of Dispersion Science and Technology
Year Published: 2017
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