mented region-wise, because it is then possible to identify a comparison group not yet invited to screening. However, screening changes the age-specific incidence in cohorts of women offered screening. This… Click to show full abstract
mented region-wise, because it is then possible to identify a comparison group not yet invited to screening. However, screening changes the age-specific incidence in cohorts of women offered screening. This includes a prevalence peak at first screen; an artificial aging at subsequent screens; and a compensatory dip after end of screening [5,6]. Therefore, studies of overdiagnosis require also that women can be followed for a sufficiently long period after end of screening for the compensatory dip to materialize. Such studies have been undertaken in for instance Florence Italy [16]; in Finland [17]; and in Denmark [18].
               
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