LAUSR

Large-vessel vasculitis (LVV) affects the aorta and its major branches, and has two major variants: Takayasu arteritis (TAK) and giant cell arteritis (GCA). TAK is a chronic disease treated with glucocorticoids, and 20% of casesmay burn out after a long-term inflammatory process or treatment (1). However, spontaneous remission without vascular complications has not been known. In addition, although thymoma and thymic carcinoma cause paraneoplastic disorders (2), only one case of LVV associated with thymoma has been reported; therefore, its clinical course is unknown (3). To our knowledge, this is the first report of two cases of LVV in which spontaneous remission occurred: one with TAK and the other potentially associated with thymic carcinoma. We obtained the patients’ written informed consent to publish the material. Case 1. A 45-year-old woman with a history of TAK presented with bilateral cervical pain and high-grade fever. At the age of 36 years, she had been diagnosed with TAK based on wall thickening and calcification of the bilateral carotid arteries; and aneurysmal dilatation of the coronary arteries, ascending aorta, and abdominal aorta; however, negative C-reactive protein (CRP) and no vascular uptake on [F]fluorodeoxyglucose-positron