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Removal of breast implants as primary treatment for autoimmune/inflammatory syndrome induced by adjuvants

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Associations between introducing adjuvants into the body and the development of autoimmune and inflammatory diseases have long been recognized. In 2011, this phenomenon was characterized as the autoim-mune/inflammatory syndrome induced… Click to show full abstract

Associations between introducing adjuvants into the body and the development of autoimmune and inflammatory diseases have long been recognized. In 2011, this phenomenon was characterized as the autoim-mune/inflammatory syndrome induced by adjuvants (ASIA) (1). However, very few studies have focused on whether explantation of these adjuvants has a role in treatment. Explantation is often performed owing to implant rupture or infection (2) rather than as a primary therapeutic option, and this may act as a confounding factor on any improvement in symptoms. Furthermore, medication changes around the time of explantation (3) may mask any effects of implant removal. We describe a patient with breast implants and autoimmune disease who showed significant improvement following explantation of implants alone. The patient fulfilled three major and two minor criteria for the diagnosis of ASIA (1).

Keywords: autoimmune inflammatory; inflammatory syndrome; induced adjuvants; breast implants; syndrome induced

Journal Title: Scandinavian Journal of Rheumatology
Year Published: 2022

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