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Is the absence of alpha-helix 2 in the appendant structure region the major contributor to structural instability of human cystatin C?

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Human cystatin C (HCC) is a 120-amino acid protein that belongs to the cystatin super family. It is expressed in all nucleated human cells and is found in almost all… Click to show full abstract

Human cystatin C (HCC) is a 120-amino acid protein that belongs to the cystatin super family. It is expressed in all nucleated human cells and is found in almost all tissues and body fluids. HCC pl...

Keywords: absence alpha; human cystatin; cystatin; structure; alpha helix; helix appendant

Journal Title: Journal of Biomolecular Structure and Dynamics
Year Published: 2018

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