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IgA negative immunofluorescence in diagnoses of adult-onset Henoch-Schönlein purpura

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Abstract We describe two cases of young adult men presenting with diffuse petechial rash and gastrointestinal disturbances. They were found to have leukocytoclastic vasculitis without immunoglobulin A findings under direct… Click to show full abstract

Abstract We describe two cases of young adult men presenting with diffuse petechial rash and gastrointestinal disturbances. They were found to have leukocytoclastic vasculitis without immunoglobulin A findings under direct immunofluorescence on skin biopsy histopathology performed over a week after the appearance of lesions. Henoch Schönlein purpura (HSP) was diagnosed based upon the clinical presentation as well as the leukocytoclastic vasculitis biopsy findings.

Keywords: henoch sch; nlein purpura; iga negative; negative immunofluorescence; sch nlein

Journal Title: Baylor University Medical Center Proceedings
Year Published: 2020

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