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Development of Vitreoretinal Lymphoma in a Patient with Sarcoid Uveitis

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ABSTRACT Purpose The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. Material and Methods A 63-year-old woman with… Click to show full abstract

ABSTRACT Purpose The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. Material and Methods A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features. Conclusion Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.

Keywords: lymphoma patient; sarcoid uveitis; lymphoma; vitreoretinal lymphoma

Journal Title: Ocular Immunology and Inflammation
Year Published: 2019

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