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Histopathology and Molecular Biology Study of an Eyeball of a Case of Acute Retinal Necrosis.

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Purpose: To report a histopathology and molecular biology study of an eyeball of a case of acute retinal necrosis (ARN).Methods: Histopathology, immunohistochemistry and molecular biology of an enucleated globe of… Click to show full abstract

Purpose: To report a histopathology and molecular biology study of an eyeball of a case of acute retinal necrosis (ARN).Methods: Histopathology, immunohistochemistry and molecular biology of an enucleated globe of acute retinal necrosis 6 years after the onset of ARN.Results: Histopathology showed persistence of chronic inflammatory cells with herpes virus inclusion body. Semi nested polymerase chain reaction showed varicella zoster virus.Conclusions: Chronic inflammatory cells and viral genome can be persistent even after 6 years after the onset of ARN.

Keywords: histopathology; acute retinal; biology; molecular biology; retinal necrosis

Journal Title: Ocular immunology and inflammation
Year Published: 2021

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