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ABSTRACT Purpose To describe the management and outcome of two extremely rare and painful cases of Mooren’s ulcer, an idiopathic peripheral autoimmune-associated ulcerative corneal disease. Methods Case report with literature… Click to show full abstract
ABSTRACT Purpose To describe the management and outcome of two extremely rare and painful cases of Mooren’s ulcer, an idiopathic peripheral autoimmune-associated ulcerative corneal disease. Methods Case report with literature review on the management of ocular inflammation in Mooren’s ulcer. Results A 47-year-old female and a 76-year-old female presented with progressive bilateral Mooren’s ulcer that were refractory to conventional immunosuppressive therapy. Following treatment with infliximab, an anti-tumor necrosis factor alpha, a significant improvement in disease progression was observed, with no corneal thinning or perforation at follow-ups. Conclusion This case report highlights how infliximab can be effective in cases with Mooren’s ulcer refractory to conventional therapies.
Journal Title: Ocular Immunology and Inflammation
Year Published: 2022
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