A 33-year-old patient, under treatment with upadacitinib for atopic dermatitis (AD), was examined for multiple, bilateral, papular, periocular lesions. The patient had AD since the age of 2 years and… Click to show full abstract
A 33-year-old patient, under treatment with upadacitinib for atopic dermatitis (AD), was examined for multiple, bilateral, papular, periocular lesions. The patient had AD since the age of 2 years and had been previously treated with topical and sys-temic agents including corticosteroids, cyclosporine, methotrexate and dupilumab. With dupilumab, the AD flared with involvement of the head and neck. Biologic treatment was inter-rupted, and upadacitinib at the dosage of 30mg/day was pre-scribed, achieving complete remission of AD signs and symptoms after 2 weeks. lymphocyte
               
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